Boston Beer Works has some of the best food around. The burgers are nice and juicy and they aren't skimpy on the meat. The locations are perfect before and after the games; right across from Fenway and on Canal Street. The crowd varies at each location, but the scene is the same. For larger crowds, the Canal Street is quite big and they have pool tables as an extra bonus if you get bored at your company party. Try the blueberry beer, it's quite different.
Pros: Beer, food, good for large crowds and children
Cons: Can get pretty loud
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