I live in NYC and travel to Chicago quite a bit for business. Whenever I go out with clients, I insist on going to ""Piece"" because the pizza is clearly the best in the world, the ambience is fantastic, and the beer is just awesome -- I get the most intense buzz after just two of those chippy micro-brews. I've been to all the so-called best pizza places in New York, New Haven, etc., but ""Piece"" blows them all away. I can talk for hours about all the gorgeous women I've picked up there too, but that's another story for another day.
Pros: Best Pizza
Cons: not open 24 hours
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