Enjoy Your Stay at One of the Best Hotels near Chicago. Located 35-miles west of Chicago, the Holiday Inn Express Hotel Chicago-St. Charles is an ideal place to kick back and relax or to take care of business. Nestled in the scenic Fox River Valley, St. Charles is an historic city with plenty of charm and the convenience of being only an hour away from the Windy City. Families love our proximity to fun attractions. You can cheer on the Kane County Cougars baseball team, tour the Fox River on an historic Paddleboat or explore quaint shops. We're located only two miles from downtown, so it's easy to come and go as you please. Guests conducting business in the area appreciate what the Holiday Inn Express Chicago-St. Charles has to offer over other hotels. In St. Charles and the surrounding area, you'll find companies like ConAgra Foods, Ball Horticultural and Siemens, as well as the Fermi National Accelerator Lab, a particle physics research hub that is seven miles away. Major convention centers are also nearby. Business travelers enjoy our 24-hour business center and complimentary copy and fax services. You can enjoy our hotel's top-rated amenities, including a 24-hour fitness center, high-speed Internet access, heated, outdoor pool and a complimentary hot breakfast bar complete with warm cinnamon rolls and great coffee. Make reservations today to take advantage of the great deals at one of the top hotels near Chicago.