Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St.. You may find yourself feeling particularly smart for choosing to stay at Holiday Inn Express.® With nearly 2,000 locations worldwide,you’ll find comfortable,inviting accommodations with just the right mix of services and amenities all at very affordable rates.
Stay Smart.® Stay at Holiday Inn Express.
With your comfort and convenience in mind:
Still free. Now hot. Express Start® Breakfast Bar
Our breakfast bar now features hot entrees as well as our exclusive cinnamon rolls and Smart Roast® Coffee.
Simply Smart Bedding Collection
Our bedding will have you waking up feeling refreshed and recharged.*
Free High Speed Internet Access
Enjoy free high-speed Internet access from your guest room. Our online concierge,eHost,is also available to assist with information about the hotel and the local area.
Simply Smart® Guest Bathroom
Featuring the Stay Smart® shower head by Kohler®.*
Priority Club® Rewards
Earn points toward free nights,airline miles,or merchandise on every qualifying stay.
*Available at Holiday Inn Express hotels in North America only