Clean. Comfortable. Efficient. The America's Best Inn Clemson SC wants to help you feel at home as much as possible when you are on the road. Experience a warm, inviting, and family-oriented lodging choice at a reasonable price at The America's Best Inn Clemson SC hotel with your complimentary breakfast, free local calls, and the opportunity to take advantage of membership in our frequent guest loyalty program. At The America's Best Inn Clemson SC - Expect More. Get More.